SMX-TMP is also one of the widely used antibiotics administered orally in neonates, along with gentamicin injection, for treating pneumonia and sepsis by home-based healthcare providers in Asian countries.
Although the use of this drug has successfully reduced neonate mortality, there is a concern for it causing neurotoxicity. Previous clinical studies with sulfisoxazole have demonstrated occurrence of kernicterus in neonates. The Manual was first published in as a service to the community. Learn more about our commitment to Global Medical Knowledge. This site complies with the HONcode standard for trustworthy health information: verify here.
Common Health Topics. Videos Figures Images Quizzes Symptoms. Infections in Neonates. Test your knowledge. Neonatal herpes simplex virus HSV infection has a high morbidity and mortality rate. The usual presenting symptom in neonates is a vesicular eruption that appears between the 1st and 3rd week of life. Bactrim Trimethoprim Sulfamethoxazole Drug Information Bactrim trimethoprim and sulfamethoxazole Bactrim is contraindicated in infants less than 2 months of age.
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